Vitamin B3, like the other B vitamins, is essential for carbohydrate breakdown into energy. Pellagra is a disabling disease that can be the result of a Vitamin B3 deficiency. According to Science Direct, Pellagra can be characterized by four “Ds”: depression, diarrhea, delirium, and dementia. It is most prevalent in developing countries where corn is the primary source of carbohydrates.
Niacin deficiency and cancer in women.
Vitamin B3, the nicotinamide adenine dinucleotides and aging.
Those who have a vitamin B3 deficiency are more prone to headaches, fatigue, depression, disorientation, and scaly pigmented rashes on skin.