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Suboptimal health, or sub-health, is characterized by symptoms such as obesity, prehypertension, pre-diabetes, borderline elevations of serum blood lipids (triglycerides or total cholesterol), renal sub-health and hepatic sub-health. Simply put, it means a risk of developing diseases related to those sub-health factors. Ideally one should treat themselves before more severe illnesses develop.


About thirty years ago in the former Soviet Union, Berkman, a scholar, first proposed a concept called "the third status". In "The International Classification of Diseases," the World Health Organization essentially defined this concept as referring to conditions of early discomfort and physical signs that do not have clear disease classifications. A Chinese scholar Wang proposed the term "suboptimal health" to describe such vague conditions. 


The difference between sub-health and disease lies not only in the diagnostic tools used to differentiate the two states but more importantly in the fact that the treating or curing of a disease once it occurs often entails medication and/or other procedures such as surgery. Sub-health can be eliminated simply by lifestyle modifications and dietary supplements. Sub-health individuals are at high risk of developing disease if not treated in time. 

About the Minerals

While the essential minerals are important for the body to function, having too much of them can also cause problems for our body. For example, manganese is a mineral that is both nutritionally essential and potentially toxic. Therefore, taking the proper amount of essential trace minerals is important. All the trace minerals in E18 follow The Adequate Intake (AI) guidelines established by the Food and Nutrition Board (FNB) of the Institute of Medicine. 


E18 is a new dietary supplement produced by Nutrition USA that has been developed through years of scientific research and is currently pending patent application. Its innovative formula includes 24 essential nutrients, including all 9 essential amino acids, which help to maintain healthy energy and vitality levels, regulate and restore various abnormal functions, and promote overall health. Recent scientific studies have shown that the combination of ingredients found in E18 may reduce the risk of Alzheimer's disease by decreasing nerve cell inflammation. This unique advantage sets E18 apart from other supplements on the market.

E18 is particularly beneficial for the elderly, who may suffer from malnutrition due to changes in digestion and absorption functions. This malnutrition can lead to sub-health problems such as fatigue, forgetfulness, and insomnia, which are often mistakenly attributed to old age. However, these problems can be easily resolved with proper supplementation of essential nutrients.

Maintaining a balanced diet is crucial for good health and a long life. By understanding scientific nutrition and diet, we can ensure that our bodies receive proper care. Along with a positive attitude and a healthy immune system, a well-rounded diet is key to improving overall health. Deficiency in essential nutrients can be fatal, highlighting the fragility of life. However, with adequate access to essential nutrients, the body can repair itself and exhibit the resilience of life.

Taking small amounts of E18 consistently while still healthy is an effective way to prevent sub-health conditions from becoming more serious and avoid the need for more serious medical interventions. By supplementing with essential nutrients, we can reduce our risk of disease and improve our overall health. Continuously taking E18 in small amounts helps the body obtain essential nutrients, boost immunity and energy levels, and prevent the onset of chronic diseases.

In short, E18 is a simple and convenient nutritional dietary supplement that can replace various other similar products in the market, providing better health effects. Following scientific knowledge of nutrition and diet, mastering a reasonable diet structure, and adopting a healthy lifestyle is the right way to maintain good health. As the saying goes, "health is wealth," and with E18, we can maintain our wealth of health for a better life.



Amino Acids - The Building Blocks

Many seniors face health challenges due to aging. One of them is malnutrition which can be caused by a poor diet along with a weakened ability to digest and absorb food. Malnutrition places seniors at a high risk of infection, fracture, depression and diminished mental alertness. 


E18 contains 20+ nutrients that help supply adequate nutrition. Among those, there are nine essential amino acids. Amino acids are among the nutrients that our body needs to build muscle, facilitate certain chemical reactions in the body, transport nutrients and prevent illness. When an older person doesn't eat well, they may eventually lack some of these essential amino acids which can result in the body producing less protein which will lead to problems in the body's basic functioning along with weight loss. Low body weight makes elderly people prone to infection and fracture. Some studies found that individuals over the age of 65 who have a low BMI may have a higher mortality risk.

Optical Problems

According to the National Eye Institute, AMD is a leading cause of vision loss among people age 50 and older. It causes damage to the macula, a small area near the center of the retina and the part of the eye needed for sharp central vision. AMD can lead to central vision loss and partial blindness. People who smoke; have a family history of AMD and are Caucasian are at a higher risk.

Vitamin A and zinc in E18 in combination can reduce the risk of Age-Related Macular Degeneration (AMD).  Vitamin A also helps the surface of the eye (cornea) to be an effective barrier against bacteria and viruses, reducing the risk of eye infections.


Osteoarthritis is an inflammatory degenerative disease of the joint affecting aging populations worldwide. The curcumin in E18 has been proven by researchers to have positive effects in combatting this disease via its ability to prevent apoptosis of the chondrocytes mainly caused by inflammation and to a lesser extent, oxidative stress.



The Female Athlete's Triad

The female athlete’s triad is made up of a group of conditions consisting of eating disorders, absence of a period and thinner bones.  Low-calorie diets are usually the first sign of eating disorders. Excessive or compulsive exercise is another sign. Young females who are thin and exercise excessively are at higher risk of amenorrhea, the absence of a period. And amenorrhea is linked to decreased estrogen levels, which may be a cause of osteoporosis.

Zinc and its Role in Menstruation

Zinc deficiency in women can lead to impaired synthesis and secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). FSH stimulates ovarian follicles to produce eggs and LH stimulates the release of the egg from the ovary. Both of these hormones play a very important role in a woman’s capacity to conceive. Zinc deficiency can result in a difficult pregnancy or frequent spontaneous abortions. 

Iron (Wo)man

Iron, one of the essential trace minerals in E18, plays an important role in women's health. As a component of hemoglobin and myoglobin, iron functions as a carrier of oxygen in the blood and muscles. Because of the loss of iron from blood loss during menstruation, women in their reproductive years (11-50 yo) require higher iron intake than men. The recommended amount of intake for women is 18mg/day according to the Recommended Dietary Allowance (RDA) for women. However, women have difficulty achieving this intake because they generally have a relatively low caloric intake, and the usual U.S. diet provides only 6 to 7 mg of iron per 1,000 calories. This means taking in 2000 calories/day results in only about 12 to 14 mg of iron. When a woman takes E18 as a supplement to her daily iron intake she will easily achieve the recommended amount of iron per day. 



Zinc and the Preservation of Testosterone

E18 contains an essential trace mineral called zinc. Zinc aids in regulating the enzyme complex aromatase by inhibiting its activation.  Aromatase converts testosterone (male hormone) into estradiol (female hormone). Zinc deficiency can cause excessive conversion of testosterone into estradiol. The depletion of testosterone results in decreased sex drive and a lower sperm count in men.

Vitamin D

Vitamin D in E18 plays an important role in prostate health. In 1990 Schwartz from the University of North Carolina hypothesized that Vitamin D deficiency may contribute to the major risks for prostate cancer, which include age, people of African descent and people who live in northern latitudes. Since then, many research studies have been conducted.  It is now well established that vitamin D inhibits the growth of normal prostatic epithelial cells, as well as primary cultures of prostate cancer cells and prostate cancer cell lines. Currently, vitamin D is part of the management of prostate cancer in many patients.

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